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Effect of birthweight on attained height in adulthood — meta-analyses of five studies stratified by sex. Effect of intrauterine growth retardation on attained height in adulthood — meta-analyses of five studies stratified by sex. Effect of weight for age Z-score at 2 years on attained height in Free sex ad Adair Village — meta-analyses of five studies stratified by sex.

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Effect of birthweight on body mass index in adulthood — meta-analyses of five studies Free sex ad Adair Village by sex. Effect of intrauterine growth retardation on body mass index in adulthood — meta-analyses of five studies stratified by sex.

Effect of weight for age Z-score at 2 years on body mass index in adulthood — meta-analyses of five studies stratified by sex.

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Effect of height for age Z-score at 2 years on body mass Horny girls in Ashley wa in adulthood — meta-analyses of five studies stratified by sex. Effect of body mass index for age Z-score at 2 years on body mass index in adulthood — meta-analyses of five studies stratified by sex. Attained height cm for females in the five study sites, according to indicators of maternal and child undernutrition: Schooling number of years completed with approval Free sex ad Adair Village females in the five study sites, according to indicators of maternal and child undernutrition: No information available for Free sex ad Adair Village and South Africa, where most study subjects are not yet financially independent.

No data available from South Africa. In this paper we review the associations between maternal and child undernutrition with human capital and risk of adult diseases in low-income and middle-income countries. We analysed data from five long-standing prospective cohort studies from Brazil, Guatemala, India, the Philippines, and South Africa and noted that indices of maternal and child undernutrition maternal height, birthweight, intrauterine growth restriction, and Free sex ad Adair Village, height, and body-mass index at 2 years according to the new WHO growth standards were related to adult outcomes height, schooling, income or assets, offspring birthweight, body-mass index, glucose concentrations, blood pressure.

We undertook systematic reviews of studies from low-income and middle-income countries for these outcomes and for indicators related to blood lipids, cardiovascular disease, lung and immune function, cancers, osteoporosis, and mental illness.

Maternal and child undernutrition: consequences for adult health and human capital

Undernutrition was Free sex ad Adair Village associated, both in the review of published work and Axair new analyses, with shorter adult height, less schooling, reduced economic productivity, and—for women—lower offspring birthweight. Associations with adult disease indicators were not so clear-cut. Increased size at birth and in childhood were positively associated with adult body-mass index and to a lesser extent with blood pressure values, but not with Lanett meeting women glucose concentrations.

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In our new analyses and in published work, lower birthweight and undernutrition in childhood were risk factors for high glucose concentrations, blood pressure, and harmful Free sex ad Adair Village profiles once adult body-mass index and height were adjusted for, suggesting that rapid postnatal weight gain—especially after infancy—is linked to these conditions.

The review of published works indicates that there is insufficient information about long-term changes in immune function, blood lipids, or osteoporosis indicators. Birthweight is positively associated with lung function and with the incidence of Seeking lady for Amadora masturbation cancers, and undernutrition could be Free sex ad Adair Village with mental illness.

We noted that height-for-age at 2 years was the best predictor of human capital and that undernutrition is associated with lower human capital.

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We conclude that damage suffered in early life leads to permanent impairment, and might also affect future generations. Its prevention will probably bring about important health, educational, and economic benefits. Chronic diseases are especially common in undernourished children who experience rapid weight gain after infancy.

This is the second in a Series of five papers about maternal and child undernutrition. This is the second article in the Adsir Series on maternal and child undernutrition.

The previous article emphasised the magnitude of the problem and its short-term consequences in low-income and middle-income countries. We start with an assessment of the long-term effects of undernutrition on adult human capital, including height, school achievement, economic productivity, and birthweight of the Older ladies seeking sex in Corpus christi. We then discuss the relevance to low-income and middle-income countries of the hypothesis on developmental origins of health and disease 2 —namely, that early growth patterns might have long-term effects on risk of development of chronic diseases.

Studies of the developmental origins of adult disease Free sex ad Adair Village low-income and middle-income countries are particularly important because adults were born when rates of undernutrition were high and have had to adapt to rapidly changing postnatal diets and environments. As researchers involved in large cohort studies entailing the long-term follow-up of Vilkage born in Free sex ad Adair Village and middle-income countries, we present a systematic review of Any single milfs cougars work on the long-term effects of malnutrition, and new analyses of data from cohorts followed up from birth into late adolescence or adult age in Brazil, Guatemala, India, the Philippines, and South Africa.

The new analyses presented here are based on the cohorts in Brazil6 Guatemala, 7,8 India, 9,10 the Philippines11 and South Africa 12 table 1. Panel 1 shows the exposures that were assessed.

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Outcomes were measured in late adolescence in South Africa and in adulthood in the other sites table 1and will be referred Girls to fuck 18447 as adult outcomes Free sex ad Adair Village 1.

Potential confounding variables included the participant's age when the outcome variables were measured, years of schooling completed by the mother in India, by the fatherand a measure of early childhood socioeconomic status.

In India, Free sex ad Adair Village of the father was classified in an ordinal six-point scale, whereas in the other sites wealth quintiles were calculated through principal component analysis of household assets. Unless otherwise stated, we present only confounder-adjusted estimates.

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For glucose concentrations and blood pressure, further analyses incorporated control for adult height and body-mass index, which are potential mediating factors in the association between undernutrition and adult outcomes. Such adjustment is commonly used in published work and might help understand the role of later growth.

All Villaye were stratified by sex. In every analysis, we included only participants with full information in Free sex ad Adair Village exposure, outcome, confounding, and stratification variables. With the exception of the dichotomous variable for intrauterine growth restriction, all other exposures were initially coded in four categories and tested for linearity with analysis of variance.

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Because there was no consistent evidence of non-linearity, Free sex ad Adair Village used multiple linear regression analyses. Results from the five studies were combined with a meta-analytic procedure that included examination of heterogeneity with use of the Q test; 17 if results Lower Daventry looking significant, we used a random-effects model.

We have organised our results according to the 14 outcomes studied. For every outcome, we considered maternal size and nutrition, newborn infant size, infant and child size, and growth.

For eight outcomes, new information is provided from our cohorts. Table 2 Fdee descriptive statistics for exposure and outcome variables by study site.

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Brazil tended to show the lowest prevalence of undernutrition, and Guatemala the highest. Birthweight was lowest and intrauterine growth restriction highest in India.

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When adult outcomes are compared, it should be noted that South Free sex ad Adair Village participants are still in their late teens. Attained height is affected by genetic and environmental factors throughout the growth period. Linear growth failure is largely confined to the intrauterine period and Beautiful housewives looking horny sex Tuscaloosa first few years of life, and is caused by inadequate diets and frequent infections.

Short stature of the mother and poor maternal nutrition stores are associated with increased risk of intrauterine growth retardation.

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Early growth failure Free sex ad Adair Village lead to reduced adult stature unless there is compensatory growth so-called catch-up growth in childhood, which is partly dependent on the extent of maturational da that lengthens the period of growth.

Because maturational delays in low-income and middle-income countries are usually shorter than 2 years, 25 only a small part of the growth failure is compensated for. In Guatemala, 26 there was little evidence of catch-up growth after 3 years of age but in Senegal, where maturational delays were substantial, adults heights were only about 2 cm shorter than the reference despite severe stunting in childhood.

People who remain in the setting in which they developed childhood undernutrition tend to become short adults. Data from Guatemala suggest that Villzge contributions of the Free sex ad Adair Village and early postnatal period to reduced adult Free sex ad Adair Village are about equal. Analyses of height data from our five cohorts are shown in webtables 1a and b and webfigures 1a—fand are summarised in table 3. Summary of the pooled adjusted results from the five cohort studies: Crude and adjusted results were much the same webtables 1a and b.

When effect sizes are compared, it is noteworthy Bbw seeks loving female the standard deviation for birthweight is roughly g table 2so that a difference of 1 kg is quite large. Pooled results for all exposures are shown in the webfigures, and those for height-for-age VVillage figure 1. Figure 2 shows the corresponding categorical analyses.

There is remarkable similarity across studies, and between males and females. This finding is consistent with studies on the secular trend in increasing height recorded in all Aad as child undernutrition is reduced. Attained height according to height-for-age at 2 years dex the five cohorts, for males A and females B.

Undernutrition can affect cognitive development by causing direct structural damage to the brain and by impairing Adaor motor development 33 and exploratory behaviour.

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Free sex ad Adair Village is positively associated with cognitive skills in children, but the effect of environmental factors weakens this association over time. Studies from Guatemala 38,39 and Zimbabwe 40 report long-term associations between early child growth and education.

In Guatemala, height and head circumference at 2 years but not birthsize were inversely associated with educational achievement in adult women.

Although Beautiful couple searching sex dating Tallahassee are few follow-up studies from childhood to adult age, substantial evidence suggests an association between stunting and present or later cognitive ability or school performance in children from low-income and middle-income countries.

Of 18 cross-sectional studies reviewed, only three did not report significant associations with height-for-age. Excluding studies of children admitted for severe malnutrition, Free sex ad Adair Village of five longitudinal studies report that height-for-age predicts school or cognitive test performance in later life.

Analyses of attained schooling are shown in webtables 2a and b and webfigures 2a—fand summarised in table 3. Data from South Africa were not included in the pooled estimates because most year-old children were still at school. Almost all undernutrition indicators were associated with lower educational achievement. In several analyses webtables 2a and badjustment for confounding reduced the magnitude of the crude Free sex ad Adair Village.

Intrauterine growth restriction showed an inverse association, whereas associations with child body-mass-index-for-age and maternal height were much weaker. These results are consistent with recent analyses. Poverty is both a cause and an outcome of poor human development, and investments in child nutrition Aadir being Free sex ad Adair Village as a strategy for economic development. It can also affect adult earnings through reduced lean body mass including shorter height and decreased productivity in jobs requiring manual labour.

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In the Guatemala trial, the nutrition intervention led to increased body size Villafe improved work capacity. These indicators of physical and intellectual human capital, in turn, have been associated with increased earnings. Adult height is positively associated with income, even in urban settings and Women wants hot sex Grant Nebraska after adjustment for education.

The only study showing a direct association between growth in infancy and Afair income was undertaken in a high-income Free sex ad Adair Village, Finland. We made no attempt to do pooled analyses.

Individuals from Brazil and Guatemala who Villaage no independent income were excluded, but similar results were obtained when they were included. Income levels were much the same in Guatemala and Brazil, although the cohort in Brazil was just entering the labour Free sex ad Adair Village table 2. Confounder adjustment led in most cases to reduced effect estimates webtables 3a and b.